Figure 7
Frequency of proposed behaviors indicating chronic spontaneous pain in the neuropathic pain literature. Bars indicate total duration (s) of the behavior (filled) and total observation time (open). All studies used surgical nerve injuries, which are not noted except in studies featuring multiple surgeries. Note that the "scratching" behavior quantified by D'Almeida et al. [16], first described in Kupers et al. [18], is defined as "a rapid vibration of the hind paw," and is probably analogous to what is defined herein as shaking/flinching. Abbreviations: CCI, chronic constriction injury; CST, complete sciatic transection; PSNL, partial sciatic nerve ligation; PST, partial sciatic transection; SNL, spinal nerve ligation. References (from top; only first author noted): D'Almeida, 1999 [16], Paccola, 2008 [61], Guttierez, 2008 [62], Mao, 1993 [63], DeLeo, 1994 [64], Vos, 1994 [65], Deseure, 2004 [66], Kupers, 1992 [67], Kupers, 1998 [18], Kawasaki, 2008 [12], Jin, 2008 [68], Robinson, 2005 [69], Dowdall, 2005 [53], Shimoyama, 2002 [70], Sato, 2001 [71], Decosterd, 1998 [72], Kim, 1997 [52], and Choi, 1994 [73].