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Figure 3 | Molecular Pain

Figure 3

From: Changes in Aβ non-nociceptive primary sensory neurons in a rat model of osteoarthritis pain

Figure 3

Pronociceptive effects in sensory tests in OA models run one month following model induction. A. OA rats displayed a significantly decreased threshold to the von Frey hair stimulation to the affected hind paw (8.78 ± 1.85 g, N = 9 in OA vs. 14.63 ± 0.23 g, N = 6 in control, P = 0.025; Student's t-test). B. Repetitive flexion and extension of the knee had no significant effect on the latency of the tail flick reflex in control rats (97.1 ± 5.2% of the baseline latency, N = 6). However, the same manipulation significantly decreased the latency of the tail flick reflex in OA rats (64.7 ± 4.9% of the baseline readings, N = 9; P < 0.001; Student's t-test).

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