Changes in Aβ non-nociceptive primary sensory neurons in a rat model of osteoarthritis pain

Molecular Pain

Table 1 Locations of receptive fields of Aβ-fiber low threshold mechanoreceptors recorded in both the OA rats and the naive control rats

Locations	Foot	Calf	Thigh	Ankle joint	Knee joint
G/F CTL ( N )	14	2	7	1	/
G/F OA ( N )	20	8	2	2	4
RA CTL ( N )	25	2	2		2
RA OA ( N )	34	3	4	3	3
MS CTL ( N )	2	12	8	/	1
MS OA ( N )	5	31	6	/	/
SA CTL ( N )	5	/	/	/	/
SA OA ( N )	7	/	/	/	/
Aβ LTM CTL ( N )	46	16	17	1	3
Aβ LTM OA ( N )	66	42	12	5	7

The locations of receptive fields of neurons included are summarized. The classification adopts only the major anatomical regions, including foot, calf, thigh, ankle joint and knee joint. Abbreviations: CTL, naïve control; OA, osteoarthritis; G/F, neurons which include field neurons and guard hair neurons; RA, rapidly adapting neurons, which include glabrous RA neurons and Pacinian neurons; MS, muscle spindle neurons; SA, slowly adapting neurons; Aβ LTM, Aβ-fiber low threshold mechanoreceptors which include G/F, RA, MS, & SA neurons.

ISSN: 1744-8069