LPC-induced cold hypersensitivity is not inhibited by BEL. A. Intraplantar administration of LPC evoked a dose-dependent cold hypersensitivity in lightly restrained rats. B. Prior administration of BEL (30-300 μg) did not inhibit the cold hypersensitivity evoked by 60 μg LPC. Data show mean ± SEM for 6 rats/group. ** p < 0.01, *** p < 0.001 vs vehicle.