Table 1 Demographic data and clinical characteristics of the study population, according to GCH1 pain protecting haplotypes.
From: Different SNP combinations in the GCH1 gene and use of labor analgesia
Non-carriers (n = 481) | Heterozygous (n = 180) | Homozygous (n = 15) | |
|---|---|---|---|
Age, years | 30.67 ± 4.9 | 31.0 ± 4.6 | 31.4 ± 5.1 |
BMI at first antenatal visit, kg/m2 | 24.2 ± 4.0 | 24.6 ± 4.3 | 22.3 ± 2.5 |
Pre-pregnancy smokers, n (%)a | 52 (11.0%) | 23 (13.1%) | 3 (21.4%) |
Married/cohabiting, n (%) | 457 (95.0%) | 169 (93.8%) | 15 (100%) |
Nulliparity, n (%) | 221 (45.9%) | 72 (40.0%) | 10 (66.7%) |
Singleton pregnancies | 476 (99.0%) | 180 (100%) | 15 (100%) |
Spontaneous start of delivery | 411 (85.4%) | 156 (86.7%) | 13 (86.7%) |
Gestational week | 39.4 ± 1.5 | 39.3 ± 1.7 | 39.9 ± 1.3 |
Duration of labor, hours | 7.4 ± 7.2 | 6.5 ± 5.7 | 6.5 ± 4.7 |
Use of oxytocin | 219 (45.5%) | 76 (42.2%) | 7 (46.7%) |
Vaginal delivery | 405 (84.3%) | 157 (87.2%) | 12 (80.0%) |
Vacuum extraction | 53 (11.0%) | 12 (6.7%) | 1 (6.7%) |
Caesarean section | 23 (4.8%) | 11 (6.1%) | 2 (13.3%) |