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Table 3 Factors associated with use of second line labor analgesia

From: Different SNP combinations in the GCH1 gene and use of labor analgesia

  

Use of second line labor analgesia

Unadjusted OR

95% CI

Adjusted OR

95% CI

Parity

Parous

130 (34.9%)

1

 

1

 
 

Nulliparous

222 (73.3%)

5.12***

3.67 - 7.14

2.68***

1.73 - 4.16

Height

  

0.98

0.96 - 1.00

0.98

0.96 - 1.00

Start of labor

Spontaneous

291 (50.2%)

1

 

1

 
 

Induced

61 (63.5%)

1.73*

1.11 - 2.70

0.63

0.32 - 1.23

Cervical dilation at arrival to the delivery unit, cma

> 5

83 (36.9%)

1

 

1

0.79 - 0.97

 

2-4

178 (56.9%)

2.26***

1.59 - 3.20

1.34

0.85 - 2.13

 

0-1

45 (78.9%)

6.42***

3.21 - 12.82

2.46*

1.05 - 5.76

Duration of laborb

0-2 hours

32 (17.6%)

1

 

1

 
 

2-5 hours

74 (45.1%)

3.85***

2.36 - 6.29

3.33***

1.92 - 5.80

 

5-10 hours

109 (66.1%)

9.12***

5.54 - 15.03

7.13***

3.87 - 13.13

 

> 10 hours

134 (87.0%)

31.41***

17.14 - 57.53

16.53***

7.68 - 35.62

GCH1 pain protecting genotype

Absent

249 (51.8%)

1

 

1

 
 

Heterozygous

92 (51.1%)

0.97

0.69 - 137

1.25

0.80 - 1.97

 

Homozygous

11 (73.3%)

2.56

0.80 - 8.16

5.11*

1.09 - 23.96

  1. a Missing cases 81
  2. b Missing cases 11