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Figure 1 | Molecular Pain

Figure 1

From: Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin

Figure 1

Arc/Arg3.1 is only expressed in the superficial dorsal horn. Light micrographs showing the distribution of neurons expressing Arc/Arg3.1 mRNA (A, B) or protein (C) in the rat spinal dorsal horn after peripheral stimulation with 25% mustard oil gauze wrapped around one hind paw for 2 hours. Note that many of the Arc/Arg3.1 labeled neurons are located in laminae I&II, and very few labeled neurons are present below lamina II. D , Fluorescent micrograph showing the expression of Arc/Arg3.1 mRNA and its colocalization with the neuronal marker NeuN. Arrowheads indicate Arc/Arg3.1 mRNA and NeuN double labeled neurons. Scale bar: 50 μm (A and D); 25 μm (B); 100 μm (C).

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Molecular Pain

ISSN: 1744-8069

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