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Figure 8 | Molecular Pain

Figure 8

From: Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats

Figure 8

Allodynia was attenuated by central administration of retigabine in rats with TMJ inflammation. Intracerebroventricular injection of retigabine (45 μg or 15 μg) as well as morphine (1 μg) as positive control raised the head withdrawal threshold from 15 to 60 min, compared with the vehicle control (p < 0.05 two way ANOVA followed by Bonferroni post-test).

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