Differential expression of ATP7A, ATP7B and CTR1 in adult rat dorsal root ganglion tissue

Molecular Pain

Table 1 Copper transporter gene expression in rat tissues determined by quantitative PCR

	Copper transporter mRNA levels (2^(-DCT) × 10⁴) in indicated tissue
	Dorsal Root Ganglion	Brain	Spinal Cord	Liver	Kidney	Intestine
ATP7B	0^d (0-1)	1^a (0-1)	1^b (0-1)	2 (1-6)	0^d (0-1)	0^d (0-1)
ATP7A	11 (7-44)	11 (7-84)	19 (5-289)	1^c (0-9)	2 (2-84)	5^a (0-43
CTR1	12 (4-323)	19 (4-38)	30 (2-81)	73 (11-275)	13 (6-243)	43 (7-353)

Values represent the median and range (in parenthesis) of determinations in six animals. Symbols indicate when gene expression was undetectable in one^a, two^b, three^c or four^d of six animals.

ISSN: 1744-8069