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Figure 5 | Molecular Pain

Figure 5

From: Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway

Figure 5

P10 rats do not develop neuropathic pain and do not show any increase in pERK expression in the RVM following SNI. Effects of SNI or sham surgery in P10 rats (N = 3 in each group), on: A/Mechanical withdrawal thresholds measured by Von Frey testing of the hind paw of the operated limb; and B/pERK expression in the RVM, 8 days after surgery. P10 rats never developed mechanical hypersensitivity and there was no difference in pERK expression in their RVM. Data show mean ± SEM.

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