Figure 1
From: Nitric oxide is negatively correlated to pain during acute inflammation
Microdialysis Study. (a) Effect of tissue injury and ketorolac treatment on pain intensity following third molar tooth extraction (p = 0.018; repeated measure two way ANOVA, n = 24 & 20 for placebo and ketorolac treatment groups, respectively). (b) Effect of tissue injury and ketorolac treatment on NO production at the site of oral surgery. Data are presented as mean ± SEM; n = 19 & 10 for placebo and ketorolac treatment groups, respectively; *indicates the first five time points were significantly different from the last four time points, p < 0.0001; contrast analysis under the mixed linear model. Raw data were not normally distributed so were transformed to ln(VAS+1) and statistical analysis were conducted on transformed data.