Figure 3

The eicosanoid signaling pathway from Ingenuity Pathway Analysis software. Only part of the pathway is shown. The highlighted genes (in yellow) were down-regulated in the 4 day CFA model of inflammatory pain. PLA2: phospholipase A2 group IVA; PTGS: prostaglandin-endoperoxide synthase 1; ALOX12, ALOX15: rat arachidonate 12/15-lipoxygenase.