Figure 3From: Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping The eicosanoid signaling pathway from Ingenuity Pathway Analysis software. Only part of the pathway is shown. The highlighted genes (in yellow) were down-regulated in the 4 day CFA model of inflammatory pain. PLA2: phospholipase A2 group IVA; PTGS: prostaglandin-endoperoxide synthase 1; ALOX12, ALOX15: rat arachidonate 12/15-lipoxygenase.Back to article page