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Table 1 Immune and inflammatory response genes down-regulated in the DRG by intraplantar CFA

From: Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping

Gene Symbol Gene Name Fold
Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 -1.6
Alox15 arachidonate 15-lipoxygenase -2.1
Bcl6 B-cell CLL/lymphoma 6 -1.6
Btk Bruton agammaglobulinemia tyrosine kinase -1.5
Ca6 carbonic anhydrase VI -1.6
Casp8 caspase 8, apoptosis-related cysteine peptidase -1.5
Cd22 CD22 molecule -2.2
Cd52 CD52 molecule -1.9
Cnr2 cannabinoid receptor 2 (macrophage) -1.7
Colec12 collectin sub-family member 12 -1.9
Cpa3 carboxypeptidase A3 (mast cell) -2.4
Ctgf connective tissue growth factor -1.6
Ctse cathepsin E -1.8
Cybb cytochrome b-245, beta polypeptide -1.6
Efna4 ephrin-A4 -1.5
F13a1 coagulation factor XIII, A1 polypeptide -1.8
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog -1.5
Hcls1 hematopoietic cell-specific Lyn substrate 1 -1.8
Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 -1.6
Ikzf1 IKAROS family zinc finger 1 (Ikaros) -1.8
Il1r2 interleukin 1 receptor, type II -1.6
Il21r interleukin 21 receptor -1.5
Il2rb interleukin 2 receptor, beta -1.6
Klra7 killer cell lectin-like receptor, subfamily A, member 7 -1.6
Lox lysyl oxidase -1.6
Npas2 neuronal PAS domain protein 2 -1.7
Odz4 odz, odd Oz/ten-m homolog 4 (Drosophila) -1.5
Pdgfrl platelet-derived growth factor receptor-like -1.7
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) -1.9
Ptgs1 prostaglandin-endoperoxide synthase 1 -1.9
Rara retinoic acid receptor, alpha -1.6
Si sucrase-isomaltase (alpha-glucosidase) -1.6
Sit1 signaling threshold regulating transmembrane adaptor 1 -1.5
Spag16 sperm associated antigen 16 -1.6
Tnfrsf14 tumor necrosis factor receptor superfamily, member 14 -1.7
Tpsb2 tryptase beta 2 -1.5
Xdh xanthine dehydrogenase -1.9