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Figure 2 | Molecular Pain

Figure 2

From: Cutaneous C-polymodal fibers lacking TRPV1 are sensitized to heat following inflammation, but fail to drive heat hyperalgesia in the absence of TPV1 containing C-heat fibers

Figure 2

CH-fibers lack heat sensitization and AM and CPM-fibers lack mechanical sensitization after inflammation. A) After inflammation, CPM-fibers encode heating of the cutaneous receptive field with significantly higher firing rates while B) CH-fibers are not different. Neither A-fibers in C) or CPM-fibers in D) responded with increased firing rates to ascending series of constant force stimuli after inflammation.

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Molecular Pain

ISSN: 1744-8069

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