Example of TRPV1-positive CPM-fiber following inflammation. Light micrographs of a L3 DRG from the ex vivo recording preparation containing a neurobiotin-filled polymodal C-fiber (CPM) immunoreactive for TRPV1. A) A Neurobiotin labeled (green) CPM neuron (arrows) recovered from the ex vivo preparation overlaps with TRPV1 immunoreactivity (red). B) Immunostaining for TRPV1 (red) shows that the same neurobiotin-filled CPM neuron in A is immunopositive for TRPV1 (arrows). Scale bar, 20 μm.