Figure 3

Effect of TNP-ATP on mean number of pERK-LI cells in the bilateral medulla and upper cervical cord following pulpal α ,β-meATP administratio n. Mean number and rostro-caudal distribution of pERK-LI cells in ipsilateral (ipsi) and contralateral (cont) Vc and C1/C2 (A), and Pa5 (C) region induced by pulpal drug application (PBS, α,β-meATP and α,β-meATP +TNP-ATP). Mean number of pERK-LI cells in ipsilateral and contralateral Vc and C1/C2 (B), and Pa5 (D) region induced by pulpal drug application (PBS, α,β-meATP and α,β-meATP +TNP-ATP) or α,β-meATP application following lidocaine injection into TMJ. Data were analyzed using one-way ANOVA with repeated measures followed by Bonferroni multiple comparison test (*: P < 0.05, **: P < 0.01).