Responses of ACC neurons to peripheral noxious mechanical pinch stimuli. (A) EPSCs evoked by pinch (ipsilateral) recorded in voltage clamp at -70 mV in a typical IM cell. (B) Action potentials evoked by pinch stimuli applied to ipsilateral (upper) and contralateral (bottom) hind paws in RS (right), IM (middle) and IB (left). These responses were obtained in the same neuron from each type. Raster plots of spontaneous and evoked action potentials in each type.