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Figure 1 | Molecular Pain

Figure 1

From: Behavioral and anatomical characterization of the bilateral sciatic nerve chronic constriction (bCCI) injury: correlation of anatomic changes and responses to cold stimuli

Figure 1

Group mean behaviors on cold plate 3-4 weeks after bCCI. Each curve begins at the average first latency and shows the cumulative total number of withdrawal responses. (A) Cumulative hind paw Lick/Guard Events at 0.3, 5 and 10°C. The sham operated rats did not demonstrate any events at 10°C, whereas both 5 and 0.3 C temperatures did elicit some events. On the other hand, bCCI rats showed evidence of increased nocifensive reflex responses at all three plate temperatures (p < 0.001; F = 90.785; df = 1; three-way ANOVA). (B) Total cold plate cumulative nocifensive reflex response duration on three plate temperatures. The sham operated rats did not demonstrate any events at 10°C, whereas both 5 and 0.3 C temperatures did elicit some events. On the other hand, bCCI rats showed increased responding at all three temperatures. Each data point is group mean +/- SEM. (p = 0.023; F = 6.181; df = 1; three-way ANOVA).

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Molecular Pain

ISSN: 1744-8069

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