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Figure 8 | Molecular Pain

Figure 8

From: Behavioral and anatomical characterization of the bilateral sciatic nerve chronic constriction (bCCI) injury: correlation of anatomic changes and responses to cold stimuli

Figure 8

Effect of bCCI on NPY peptide staining in superficial dorsal horn. (A) Representative photomicrographs of dorsal horn immunoreactivity for Neuropeptide Y (NPY) in sham operated rats (Sham NPY) versus bCCI rats on post-ligation day 15. (B) Dorsal horn staining densitometry for NPY at various times post-ligation compared to staining in naive rats. NPY peptide showed a consistent statistically significant increase in immunoreactivity (p = 0.003; F = 11.78; df = 1; two-way ANOVA) with maximal increase on post operative day 15. Results were statistically significant for day 15 (p = 0.007; post hoc Tukey test) and day 30 (p = 0.023; post hoc Tukey test). Data points are group means +/- SEM.

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Molecular Pain

ISSN: 1744-8069

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