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Table 1 Correlation/regression analysis for anatomic marker densitometry values vs. cold behavior at postoperative day 45.

From: Behavioral and anatomical characterization of the bilateral sciatic nerve chronic constriction (bCCI) injury: correlation of anatomic changes and responses to cold stimuli

Receptor/Peptide

Acetone

L/G events

L/G duration

L/G latency

Place preference crossover

Place preference cold time

CCK

R = 0.84;

p = 0.0086

R = 0.94;

p = 0.0005

R = 0.89;

p = 0.002

R = 0.93,

p = 0.006

R = 0.79;

p = 0.01

R = 0.86;

p = 0.005

MOR

R = 0.46;

P = 0.24

R = 0.6;

P = 0.11

R = 0.68;

P = 0.06

R = 0.67;

P = 0.06

R = 0.6;

P = 0.11

R = 0.56;

P = 0.14

NPY

R = 0.21;

p = 0.6

R = 0.28;

p = 0.48

R = 0.22;

p = 0.59

R = 0.16;

p = 0.7

R = 0.5;

p = 0.2

R = 0.43;

p = 0.28

NK-1R

R = 0.71;

p = 0.04

R = 0.83;

p = 0.009

R = 0.86;

p = 0.005

R = 0.85;

p = 0.006

R = 0.79;

p = 0.01

R = 0.74;

p = 0.03

  1. Highly significant and strong correlations were found between CCK and or NK-1 R and all 6 cold behaviour tests responses (acetone, thermal cold plate 0.3°C lick/guard events; duration and latency and thermal place preference (0 vs. 45°C) crossovers and cold time. MOR and NPY did not demonstrate statistically significant correlations. L/G = lick/guard