Figure 3From: Inter-strain differences of serotonergic inhibitory pain control in inbred mice Nociception in the Spared Nerve Injury model of neuropathic pain in four inbred mouse strains. A, C. Time courses and B, D Box Plots of the areas under the curve (time × percentage change) of paw withdrawal latencies in dynamic von Frey and Cold Plate tests in C57BL/6J, 129 Sv, DBA/2J and Balb/c mice before and after sciatic nerve injury in the SNI model. Time course data are means ± s.e.m of n = 8 in each group. Surgery was performed at time "zero" after determination of baseline behavior. Boxes represent the 25th-75th percentile, the line represents the median, the dashed line the mean, whisker show the 5th-95th percentile. The asterisk indicates statistically significant differences between strains, with P < 0.05.Back to article page