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Figure 3 | Molecular Pain

Figure 3

From: Inter-strain differences of serotonergic inhibitory pain control in inbred mice

Figure 3

Nociception in the Spared Nerve Injury model of neuropathic pain in four inbred mouse strains. A, C. Time courses and B, D Box Plots of the areas under the curve (time × percentage change) of paw withdrawal latencies in dynamic von Frey and Cold Plate tests in C57BL/6J, 129 Sv, DBA/2J and Balb/c mice before and after sciatic nerve injury in the SNI model. Time course data are means ± s.e.m of n = 8 in each group. Surgery was performed at time "zero" after determination of baseline behavior. Boxes represent the 25th-75th percentile, the line represents the median, the dashed line the mean, whisker show the 5th-95th percentile. The asterisk indicates statistically significant differences between strains, with P < 0.05.

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