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Figure 1 | Molecular Pain

Figure 1

From: Z-360, a novel therapeutic agent for pancreatic cancer, prevents up-regulation of ephrin B1 gene expression and phosphorylation of NR2B via suppression of interleukin-1 β production in a cancer-induced pain model in mice

Figure 1

Ephrin B1 and Eph B1 receptor gene expression in DRGs from cancer-induced pain mouse model. B16/BL6 melanoma cells were injected into the plantar region of the right hind paw of C57BL/6 mice. L4-5 dorsal root ganglion (DRG) samples were taken on day 15 after transplantation. Gene expression analyses for ephrin B1 (A) and the Eph B1 receptor (B) were performed by quantitative real-time RT-PCR. Data represent fold changes versus the mean for normal mice. Columns represent the mean ± S.E. (n = 6). ###, p < 0.001, normal versus B16/BL6 melanoma (t-test).

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Molecular Pain

ISSN: 1744-8069

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