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Figure 4 | Molecular Pain

Figure 4

From: Inflammatory nociception diminishes dopamine release and increases dopamine D2 receptor mRNA in the rat's insular cortex

Figure 4

D1 and D2 mRNA levels were semi-quantified by RT-PCR and related to G 3 PDH mRNA. Values are the ratio of D1 or D2 cDNA/G3PDH and expressed as the mean ± SEM calculated as % of control (thermonociception) control values (C = 100%). Frame (A) shows an increase in dopamine D2 receptor mRNA levels in the group with inflammation (188 ± 3.2%) with respect to 100% of the control (p = 0.000). Frame (B) shows a decrease in dopamine D1 receptor mRNA levels in the group with inflammation (72 ± 1.6%) with respect to the control (100%, p = 0.000). At the top of each bar, there is an example of the electrophoresis agarose gel showing the control oligonucleotide (upper band) and the cDNA of D1R's in (B) and D2R's in (A) (lower band).

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Molecular Pain

ISSN: 1744-8069

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