Histological verification of the microdialysis cannula. (A) Cannula position in three different experiments. The figures show the guide cannula (red arrow) and membrane trace (black arrow). Notice that the membrane location (black arrow) involves the three regions of the insular cortex (granular, GI; dysgranular, DI; and agranular, AI). (B) A close up of the left IC was superimposed to an image from the atlas by Paxinos and Watson (1998) in order to define the location of the microdialysis probe. The piriform cortex (Pi) is in the ventral border of the IC which corresponds to the AI. The upper limit, corresponding to the GI, is attached to the upper lip region of S1 (S1ULp). The medial border comprising the three regions of the IC corresponds to the claustrum (Cl).