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Table 5 Structures fulfilling criteria 1, 2 and 3 are defined as Aδ-predominant structures

From: "First pain" in humans: convergent and specific forebrain responses

  

Criteria

  

1

2

3

1 & 2 & 3

Structure

Side

Grp level

51 > 41

Latency

 

L Thal

C

  

*

 
 

I

 

*

*

 

M Thal

C

 

*

*

 
 

I

 

*

  

Anterior insula

C

*

*

*

*

 

I

*

*

*

*

Posterior insula

I

*

*

*

*

POFC

C

*

   
 

I

*

*

  

aMCC

C

*

   
 

I

 

*

*

 

pACC

C

*

 

*

 
 

I

*

*

  

S2

C

*

 

*

 

Hypothalamus

I

*

 

*

 

Hippocampus

C

*

*

*

*

  1. Structures fulfilling three criteria for being Aδ-predominant are marked with *. Criteria are 1. Significant activation at group level after 51°C stimulation. 2. 51°C activation significantly larger than 41°C activation. 3. 51°C peak BOLD latency < 41°C peak BOLD latency. C: contralateral to stimulus, I: ipsilateral to stimulus.