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Figure 5 | Molecular Pain

Figure 5

From: Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain

Figure 5

Time-dependent [3 H]-gabapentin binding in DRG of PSL mice. (A) Concentration dependence of [3H]-gabapentin binding to soluble fraction of contralateral and ipsilateral DRG. Segments of DRG were prepared at 17:00 and 5:00. Values are shown as means with S.E.M. (n = 3). (B) Estimated maximum binding capacity (B max ) of [3H]-gabapentin to soluble fraction of DRG of PSL mice and its affinity constants (K d ). Values are shown as means with S.E.M. (n = 3). *P < 0.05 compared between two groups.

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Molecular Pain

ISSN: 1744-8069

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