Figure 7

Time-course of the antinociceptive effect of PK20 after i.v. administration (4 mg/kg and 10 mg/kg, respectively) vs. intravenously administered of 0.9% NaCl solution. Each column represents mean ± SEM of 6 - 8 animals. *p < 0.05; **p < 0.001, significantly different from saline-injected mice.