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Figure 4 | Molecular Pain

Figure 4

From: ASIC3 Channels Integrate Agmatine and Multiple Inflammatory Signals through the Nonproton Ligand Sensing Domain

Figure 4

Arachidonic Acid (AA) Potentiates AGM-Induced ASIC3 Channel Activation. (A) Representative traces showing currents induced by AA (10 μM, dark grey), AGM (1 mM) in the absence (black) or presence (light grey) of AA (10 μM). (B) Pooled data as shown in (A). Data points are means ± S.E.M. of five measurements normalized to AGM (1 mM)-induced current (dashed line). Expected value is the linear summation of normalized currents induced by AA (10 μM) and AGM (1 mM) individually. **p < 0.001.

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