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Figure 6 | Molecular Pain

Figure 6

From: Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus

Figure 6

TMJ inflammation does not affect the activation state of GFAP+ astroglial cells in the CNS. (A, C) Densitometric quantification of GFAP immunoreactivity in the trigeminal subnucleus caudalis (A) and the cervical dorsal horn (C) revealed no changes between the contralateral (contra) and the ipsilateral (ipsi) sides of CFA inflamed rats. The mean values of pixel intensity have been normalized to the contralateral side of saline injected rats, set to 1.0. Since no significant differences between saline-injected rats at 24 h and 72 h have been observed, data have been pooled together, and shown here as "saline". (B-B'', D-D'') No changes in astroglial cell morphology in the trigeminal subnucleus caudalis (delimited by the dotted line; B-B'') and the cervical dorsal horn (D-D'') were seen. Scale bars: 20 μm.

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