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Figure 8 | Molecular Pain

Figure 8

From: Temporomandibular joint inflammation activates glial and immune cells in both the trigeminal ganglia and in the spinal trigeminal nucleus

Figure 8

P2Y 12 receptor levels in the CNS are not affected by the induction of TMJ inflammation. (A, C) Densitometric quantification of P2Y12 receptor immunoreactivity in both the trigeminal subnucleus caudalis (A) and the cervical dorsal horn (C) revealed no changes between the contralateral (contra) and the ipsilateral (ipsi) sides of inflamed rats. The mean values of pixel intensity have been normalized to the contralateral side of saline injected rats, set to 1.0. Since no significant differences between saline-injected rats at 24 h and 72 h have been observed, data have been pooled together, and shown here as "saline". (B, D) Immunostaining of the P2Y12 receptor subtype in the trigeminal subnucleus caudalis (delimited by the dotted line; B-B'') and the cervical dorsal horn (D-D''). Scale bars: 20 μm.

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Molecular Pain

ISSN: 1744-8069

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