GSE increases basal MKP-1 expression in neurons and glia in the TNC. Sections of spinal cord were obtained from untreated animals (CON) or animals treated with GSE (GSE). (A) Images of a section of spinal cord stained for MKP-1 are shown in the top panels. The bottom panels represent the same sections co-stained with MKP-1 and DAPI. (B) The average fold change ± SEM of MKP-1 staining intensity from control values is reported (n = 3 independent experiments) * P < 0.01 when compared to control levels. Magnification bar = 50 μm.