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Figure 6 | Molecular Pain

Figure 6

From: DREAM regulates BDNF-dependent spinal sensitization

Figure 6

L1 mice lack sensitization. (A and C) The number of spikes in ventral root responses to single dorsal root stimuli of increasing intensities and (B and D) to trains of C-fiber intensity stimuli is shown. Responses in spinal cords from non-treated (Control) and carrageenan-treated (Inflammation) wild type mice (wt) and L1 mice are shown. Inflammation produced significantly increased responses in wild type (n = 6, overall ANOVA P < 0.01), but not in L1 (n = 5) spinal cords.

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