Figure 6From: DREAM regulates BDNF-dependent spinal sensitization L1 mice lack sensitization. (A and C) The number of spikes in ventral root responses to single dorsal root stimuli of increasing intensities and (B and D) to trains of C-fiber intensity stimuli is shown. Responses in spinal cords from non-treated (Control) and carrageenan-treated (Inflammation) wild type mice (wt) and L1 mice are shown. Inflammation produced significantly increased responses in wild type (n = 6, overall ANOVA P < 0.01), but not in L1 (n = 5) spinal cords.Back to article page