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Figure 2 | Molecular Pain

Figure 2

From: Abnormal nociception and opiate sensitivity of STOP null mice exhibiting elevated levels of the endogenous alkaloid morphine

Figure 2

Quantification of the morphine contents in different mouse brain areas of WT and STOP null mice using a morphine-specific ELISA. Amounts of endogenous morphine (ng) present in the cerebellum, brainstem and the remaining brain tissue, per gram of wet tissue. The values correspond to the morphine amount determined for STOP null (n = 10 animals; white bars) and WT (n = 13 animals; grey bars) mice in different cerebral areas as indicated. For spinal cord, the values correspond to the morphine amount determined for STOP null (n = 9 animals; white bars) and WT (n = 9 animals; grey bars) mice. Amounts of eM in the STOP null and WT groups were found statistically different (mean +/- SD, Mann-Whitney test using Bonferroni correction; **: p < 0.01; ***: p < 0,001).

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Molecular Pain

ISSN: 1744-8069

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