Figure 8From: Preserved acute pain and impaired neuropathic pain in mice lacking protein interacting with C Kinase 1 L 5 spinal nerve ligation (SNL) does not induce GluR2 internalization in dorsal horns from wild-type (WT) mice. A, GluR2 levels in the cytosolic fraction from the ipsilateral dorsal horns of WT and PICK1 knockout (KO) mice at different time points after L5 SNL. Top: Representative Western blots. Bottom: Statistical summary of the densitometric analysis expressed relative to naïve (0) mice after normalization to corresponding β-actin. B, GluR2 levels in the synaptosomal membrane fraction from the ipsilateral dorsal horn of WT and PICK1 KO mice at different time points after L5 SNL. Top: Representative Western blots. Bottom: Statistical summary of the densitometric analysis expressed relative to naïve (0) mice after normalization to corresponding N-cadherin.Back to article page