Figure 2
From: Neuropathic Nav1.3-mediated sensitization to P2X activation is regulated by protein kinase C
P2X activation triggers action potentials in neuropathic DRG neurons. (A) Representative traces obtained in current clamp recordings at resting membrane potential (no current injection), and action potentials induced by the application of increasing concentrations of α,β-meATP. (B) Percentage of naïve and neuropathic DRG neurons that generated action potentials in response to increasing concentrations of α,β-meATP. (N = 8-15, all cells were pooled).