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Table 1 Pain-related target genes predicted for miR-1, -16, -122, and -206 from in silico analysis.

From: Differential expression of microRNAs in mouse pain models

Putative target NCBI reference microRNA PicTar score MicroCosm score TargetScan score Reference
Bdnf NM 007540 1, 16, 122, 206 12.6, 13.9, x, 8.7 x, x, 15.9, x -0.23, x, x, -0.23 [5254]
Mapk3 NM 011952 1, 16, 122 x, 5.9, x x, x, 15.5 -0.21, x, x [55]
Calm2 NM 007589 1, 122, 206 5.6, 3.3, 6.6   -0.20, x, x [56, 57]
Ngfr NM 033217 1, 206    -0.06, x, -0.06 [5860]
Pla2g4a NM 008869 1, 206   17.4, 16.9 -0.34 [6163]
Igf1 NM 010512 1, 206 3.1, 2.3   -0.47, x [64, 65]
Trpc3 NM 019510 16   16.1   [66]
Oprd1 NM 013622 122    0.01 [67, 68]
  1. Genes, and the corresponding regulatory miRNAs predicted according to PicTar (27), MicroCosm Target version 5 (internet available at http://www.ebi.ac.uk/enright-srv/microcosm), and TargetScan (28) databases. For each predicted gene the NCBI number, predicted microRNA, PicTar score, MicroCosm score, TargetScan score, and pain-related references are provided. Larger PicTar scores, higher MicroCosm scores, and more negative TargetScan scores indicate high-likelihood of encoding a target containing conserved 3' UTR sequences; x corresponds to non-identified target in the database.