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Figure 1 | Molecular Pain

Figure 1

From: Peripheral effects of morphine and expression of μ-opioid receptors in the dorsal root ganglia during neuropathic pain: nitric oxide signaling

Figure 1

Antiallodynic effects of morphine. Effects of the subplantar administration of different doses (logarithmic axis) of morphine or vehicle on the mechanical (A) and thermal allodynia (B) induced by CCI in the ipsilateral paw of WT mice at 21 days after surgery. Morphine was administered 20 min before starting behavioral testing. Data are expressed as mean values of maximal possible effect (%) for mechanical allodynia and inhibition (%) for thermal allodynia ± SEM (5-6 animals for dose). In both tests, for each dose, * P < 0.05 and *** P < 0.001 denote significant differences between morphine and vehicle treated animals (Student's t test).

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