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Figure 3 | Molecular Pain

Figure 3

From: Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice

Figure 3

Oxaliplatin (OHP) decreases NCV in caudal and digital nerves. (a) Mice treated with oxaliplatin 3.5 mg/kg/iv twice weekly for four weeks (gray bars; n = 8) had a significant decrease in caudal NCV compared to naïve mice (black bars; n = 8). (b) The oxaliplatin-treated mice had a significant decrease in caudal nerve action potential amplitude compared to naïve mice. (c) The oxaliplatin-treated mice had a significant decrease in digital NCV compared to naïve mice. (d) The oxaliplatin-treated mice had no difference in the amplitude of the digital nerve action potential compared to naïve mice. **p < 0.0001 vs. naive, #p < 0.001 vs. naive, Student's T Test.

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Molecular Pain

ISSN: 1744-8069

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