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Table 1 Oxaliplatin increases activity of wide dynamic range neurons in the spinal dorsal horn.

From: Multimodal assessment of painful peripheral neuropathy induced by chronic oxaliplatin-based chemotherapy in mice

Treatment

Mice

Neurons

Brush

Press

Pinch

Acetone

   

Spikes

(SEM)

Spikes

(SEM)

Spikes

(SEM)

Spikes

(SEM)

Naive

n = 6

n = 20

24.47

(4.62)

25.78

(5.92)

46.56

(9.97)

13.92

(3.01)

Oxaliplatin

n = 6

n = 23

64.93

(6.27)**

70.59

(11.17)**

123.38

(14.77)**

43.09

(9.16) #

  1. The peak number of spikes per second were higher in the oxaliplatin-injected mice compared with naïve mice. **p < 0.001 and #p < 0.01 vs. naive, Student's T Test.
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Molecular Pain

ISSN: 1744-8069

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