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Figure 6 | Molecular Pain

Figure 6

From: Local activation of cannabinoid CB1 receptors in the urinary bladder reduces the inflammation-induced sensitization of bladder afferents

Figure 6

Bladder immunoreactivity for CB 1 receptor (A, B) and TRPV1 (C, D). Mice were injected with saline (control, A, C and E) or cyclophosphamide (CYP, B, D and F) 300 mg/kg two hours before tissue harvest. Arrowheads = nerve fibres which co-express CB1 receptors and TRPV1, U = urothelium, L = lumen, dotted line = separation between the suburothelial (SU) and the muscular (M) layers. The boxes focus on the co-expression of CB1 with TRPV1 in fibers of the suburothelium layer, scale bar = 20 μm.

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