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Figure 4 | Molecular Pain

Figure 4

From: Activation of ATP-sensitive potassium channels antagonize nociceptive behavior and hyperexcitability of DRG neurons from rats

Figure 4

K ATP opener activates glyburide-sensitive currents in DRG neurons. (A) Representative current traces recorded from a small diameter DRG neuron using the voltage protocol shown at the top. Perforated whole-cell patch clamp was used. Effects of pinacidil (Pin) and pinacidil (Pin) plus glyburide (Gly) were indicated. (B) The time course of currents recorded at -20 mV and -140 mV from a small diameter neuron. Effects of KATP openers and blocker were indicated.

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