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Figure 6 | Molecular Pain

Figure 6

From: Monosodium iodoacetate-induced joint pain is associated with increased phosphorylation of mitogen activated protein kinases in the rat spinal cord

Figure 6

Comparisons of MIA-induced contralateral paw allodynia to spinal ERK phosphorylation. Mechanical allodynia, measured as withdrawal threshold (***p < 0.001 vs. naïve control), was observed on the contralateral paw 3-wk following MIA (A). In the 3-wk MIA-treated rats, ERK phosphorylation was observed in both ipsilateral and contralateral dorsal horn spinal when immunohistochemically evaluated immediately following allodynia testing (B). ERK1/2 phosphorylation data are represented as mean values (± S.E.M) of the percent of ipsilateral naïve control rats; ** p < 0.01 vs. naïve controls (Fisher's PLSD post hoc analysis); n = 5-7/group.

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Molecular Pain

ISSN: 1744-8069

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