Figure 4
From: Glial TNFα in the spinal cord regulates neuropathic pain induced by HIV gp120 application in rats
Immunohistochemistry shows TNFα immunostaining in the whole spinal cord in rats with application of gp120 into the sciatic nerve. Fourteen days after gp120 application, a substantial increase in the intensity of TNFα immunostaining was observed in the ipsilateral L4/5 spinal cord. The most prominent increase was found in the medial laminas I-IV of the dorsal horn, but the deep dorsal horn (laminas V and VI) and the ventral horn also showed an increase in TNFα immunostaining.