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Table 2 Brain Region of activities related to Minimal(MI-EA) and Optimal(OI-EA) intensities of EA (Rt: right; Lt: Left; SI: Primary somatosensory cortex; SII: Secondary Somatosensory cortex)

From: The analgesic effect of electroacupuncture on acute thermal pain perception-a central neural correlate study with fMRI

EA Intensity Mode

Regions of Activities

(Peak t-value)

BA (cluster size)

Peak coordinate

x, y, z

 

Activation

MI-EA

Rt. Inferior frontal cortex (14.92)

44(3453)

47,10,1

 

Rt. Dorsal lateral prefrontal cortex(10.71)

46(3233)

45,13,21

 

Rt. Caudate Nucleus(6.40)

(270)

17,3,0

 

Lt. inferior frontal lobe(6.98)

44 (1514)

-31,22,12

 

Deactivation

MI-EA

Rt. SI (-5.15)

1(324)

29,-35,48

 

Rt. SII (-5.37)

5(374)

17,-42,51

 

Rt. Thalamus (-5.02)

(627)

4,-3,10

 

Rt. cingulate cortex (-4.12)

31(15465)

-13,-47,33

 

Rt. Frontal lobe(-4.57)

9(591)

11,55,42

 

Lt. Frontal lobe(-8.13)

31(8778)

-7,-70,21

 

Rt.SII(-4.81)

7(520)

14,-58,36

 

Rt. Frontal lobe(-4.37)

10(272)

5,67,27

 

Lt. Frontal lobe(-4.76)

10(325)

-4,67,9

 

Lt. SII(-4.59)

7(277)

-7,-63,48

 

Lt. Frontal lobe(-5.10)

10(540)

-10,56,37

 

Activation

OI-EA

No significant finding

 

Deactivation

OI-EA

Rt. SII(-4.70)

7(273)

38,-68,57

 

Lt. Anterior cingulate cortex(-4.20)

32(565)

-10,28,17

 

Lt. Premotor cortex(-4.74)

8(2240)

-13,31,45

 

Lt. Premotor cortex (-5.45)

6(420)

-25, 13,57

 

Lt. Raphe nucleus(-5.77)

(1156)

-1,-20,-15

 

Lt. Parietal lobe(-4.41)

39 (374)

-55,-47,48

 

Rt. Amygdala (-5.512)

(248)

-68,-75,15

 

Lt. Amygdala (-4.91)

(173)

-43,-11,-36