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Figure 7 | Molecular Pain

Figure 7

From: Glutamate acts as a neurotransmitter for gastrin releasing peptide-sensitive and insensitive itch-related synaptic transmission in mammalian spinal cord

Figure 7

The characterization of itch-induced FosGFP-expressing neurons in the spinal cord after intradermal histamine injection in FosGFP transgenic mice. (A) The evoked responses by DREZ stimulation on FosGFP-expressing neurons of the spinal cord (a) were blocked by a bath application of CNQX (25 μM) (b&c). The summarized amplitudes of evoked EPSCs before and after CNQX application was shown in (d) (n = 5). (B) A bath application of GRP (300 nM for 2 min) elicited action potential firing on one FosGFP-expressing neuron in the spinal cord.

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