Skip to main content
Figure 2 | Molecular Pain

Figure 2

From: Streptozotocin-Induced Early Thermal Hyperalgesia is independent of Glycemic State of Rats: Role of Transient Receptor Potential Vanilloid 1(TRPV1) and Inflammatory mediators

Figure 2

Changes in blood glucose levels, body weight, glucose tolerance, plasma insulin levels, thermal pain sensitivity, mechanical allodynia in STZ-treated normoglycemic (STZ-NG) rats. A. Blood glucose levels (BGL) remained constant throughout the course of the experiment in STZ-NG and vehicle-treated rats. B. The body weight of STZ-NG rats (filled circles, n = 12) and vehicle-treated rats (filled squares, n = 10) increased steadily over the course of 5 weeks C. Glucose tolerance test (GTT) in STZ-NG and vehicle-treated rats after 5 weeks of STZ administration. D. Plasma insulin levels were unchanged in STZ-NG rats as compared to vehicle-treated rats. E. STZ-NG rats exhibited a significant decrease (p < 0.05) in PWL as compared to vehicle-treated rats. F. STZ-NG rats exhibited a significant (p < 0.05) decrease in PWT after 3 weeks of STZ administration as compared to vehicle-treated rats. Asterisk (*) represent p < 0.05.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us