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Figure 1 | Molecular Pain

Figure 1

From: Highly localized interactions between sensory neurons and sprouting sympathetic fibers observed in a transgenic tyrosine hydroxylase reporter mouse

Figure 1

Sympathetic sprouting onto DRG observed in fixed whole mount preparation after staining for TH. TH staining is indicated in red using conventional immunohistochemistry. Arrows indicate the location of the dorsal ramus. In these low power whole mount views, the ventral and dorsal rami of the spinal nerve are to the left (in vivo the dorsal ramus would be perpendicular to the plane of the picture; it is flattened against the ventral ramus in the process of fixing the whole mount DRG preparation). Lower magnification (left; Scale bar = 100 μm) and higher magnification (right; scale bar 20 μm) views on the indicated POD are shown. "POD 3 + dorsal ramus cut", in this experiment the dorsal ramus was cut along with the ventral ramus; in all other POD figures the conventional spinal nerve ligation was done in which only the ventral ramus was cut.

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Molecular Pain

ISSN: 1744-8069

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