Figure 6
TC-2559 has no effect on sEPSCs in the superficial dorsal horn of the spinal cord slices. A, Whole-cell voltage-clamp (Vh = -70 mV) recording of sEPSCs in a SG neuron before and after bath application of 2 μM TC-2559. B-C, Normalized rate histogram showing the mEPSC frequency (B) and amplitude (C) before and during bath application of 2 μM TC-2559 (n = 18). D-E, 2 μM TC-2559 had no significant effect on both the frequency (D, P = 0.3065, n = 18) and amplitude (E, P = 0.7442, n = 18) of sEPSC (Paired t test).