Figure 3

Quantitative analysis of lentivector transduction efficiency in primary DRG cultures. Quantification of transduction rates for neurons (identified by β3-tubulin antibody) and glia (identified by glutamine synthetase antibody) in primary dissociated DRG cultures demonstrated vector-specific efficacy for VSV-G pseudotyped vectors containing UbC, CAG, and EF1α promoters and a RABPV pseudotyped vector with the EF1α promoter. Post hoc differences between transduction rates are represented by bars; * p < 0.001. (There were no differences in glial transduction rates between the different vectors.)