Figure 2
From: Ensemble encoding of nociceptive stimulus intensity in the rat medial and lateral pain systems
Neuronal responses in the medial (ACC, MD) and lateral (SI, VPL) pain pathways induced by laser stimulation. (A) Cluster plot depicting the temporal distribution patterns of neuronal activity in response to laser stimulation. The firing rates were transferred into Z-scores and neurons with Z-scores > 2 were accepted as significantly excited and < -2 as significantly inhibited. The colorbar legend ranges from light yellow for highest Z-score to light blue for lowest Z-score. Each line in the image represents the normalized activity of one neuron. (B) Raster and peri-event histograms showing various types of neuronal responses in the ACC, MD, SI, and VPL. Each dot in the raster (top) depicts the time of occurrence of a neuronal spike, with each row representing an individual trial. The peri-event histogram (bottom) illustrates the average firing rate of a neuron relative to the laser stimulation. Time = 0 on the x axis corresponds to the the laser stimulation onset. Insets show spike waveforms from each recording. (C) A representative example of an ACC neuron whose activity increased with stimulus intensity (120-180 mJ).